- Basic information
- CohesinDB ID: CDBP00417974
- Locus: chr21-35120189-35121289
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Data sourse: ENCSR000BLD, ENCSR167MTG, GSE67783, ENCSR000BKV, ENCSR000FAD, GSE72082, GSE86191, GSE76893, ENCSR000BLS, GSE105028, GSE206145-NatGen2015, ENCSR000ECE, ENCSR054FKH, GSE206145, ENCSR153HNT, GSE116344, GSE25021, ENCSR000EDW, GSE97394
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Cell type: RPE, H1-hESC, Fibroblast, HCT-116, RH4, Hep-G2, HUES64, K-562, HSPC, H9-hESC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 5% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.889
- Subunit: SA1,Rad21,SMC1,SA2,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
84% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 79%,
"14_ReprPCWk": 9%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: NFIA, SMC1A, ZNF263, POU5F1, TOP2A, ZFX, XBP1, ZNF317, DUX4, WT1, ZBTB48, ERG3, HOXB13, ZFHX2, ERG, YY1, RELA, ATF3, MYC, RUNX2, ZFP64, NFIC, RAD21, GRHL3, NFIB, ATF2, GABPA, STAT3, MAX, XRCC5, GATA1, ZNF143, NFE2, ZNF398, MED1, EZH2, KLF9, C11orf30, EGR2, CTCF, BCL11A, AR, REST, SIX2, BRD4, JUND, CLOCK, ZNF316
- Target gene symbol (double-evidenced CRMs): RUNX1,SMIM11A
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000205670,
ENSG00000159216,
- Related loop:
chr21:34350000-34375000~~chr21:35100000-35125000,
chr21:34350000-34375000~~chr21:35125000-35150000,
chr21:34875000-34900000~~chr21:35125000-35150000,
chr21:35000000-35025000~~chr21:35100000-35125000,
chr21:35100000-35125000~~chr21:35300000-35325000,
chr21:35100000-35125000~~chr21:35825000-35850000,
chr21:35100000-35125000~~chr21:35925000-35950000,
chr21:35125000-35150000~~chr21:35250000-35275000,
chr21:35125000-35150000~~chr21:35375000-35400000,
chr21:35125000-35150000~~chr21:35825000-35850000,