- Basic information
- CohesinDB ID: CDBP00417977
- Locus: chr21-35128598-35129121
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Data sourse: GSE85526, ENCSR000EDE, GSE116344, GSE108869, ENCSR000ECS
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Cell type: HeLa-S3, RH4, HEKn
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SMC3,Rad21,SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
84% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 73%,
"9_Het": 13%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, FOSL1, SOX2, XBP1, FOXA1, ATF3, CHD7, TP63, ZNF287, TEAD1, TRIM28, ELF1, SNAI2, LMO2, HNF1B, JUN, CTCF, EP300, RFX5, DEK, ZNF528, ZNF350, TEAD4, PDX1, POU2F2, POU5F1, TOP2A, ID3, RUNX1T1, HOXC5, ERG, ONECUT1, MYC, RAD21, LHX2, GABPA, STAT3, RCOR1, NR3C1, CEBPB, FEZF1, GRHL2, ELF4, SPI1, IRF1, GATA2, SIX2, RUNX1, SMC1A, CEBPA, ZFX, SMAD3, RUNX2, PBX4, NRF1, CBFA2T3, FOS, CDK8, MYB, SCRT2, EVI1, NIPBL, SP1, BCL11A, ZHX1, PHIP, SMC3, PAX7, FOXA2, CBX3, CHD2, MEIS1, ZSCAN16, MAFF, HOXB13, YY1, RELA, GATA3, TAL1, MAX, ZNF143, KLF4, TCF7L2, ZNF334, ELF3, AR, EGLN2, BRD4, JUND, SCRT1, FOSL2
- Target gene symbol (double-evidenced CRMs): SMIM11A,RUNX1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000205670,
ENSG00000159216,
- Related loop:
chr21:34350000-34375000~~chr21:35100000-35125000,
chr21:34350000-34375000~~chr21:35125000-35150000,
chr21:34875000-34900000~~chr21:35125000-35150000,
chr21:35000000-35025000~~chr21:35100000-35125000,
chr21:35100000-35125000~~chr21:35300000-35325000,
chr21:35100000-35125000~~chr21:35825000-35850000,
chr21:35100000-35125000~~chr21:35925000-35950000,
chr21:35125000-35150000~~chr21:35250000-35275000,
chr21:35125000-35150000~~chr21:35375000-35400000,
chr21:35125000-35150000~~chr21:35825000-35850000,