- Basic information
- CohesinDB ID: CDBP00417980
- Locus: chr21-35134063-35134780
-
Data sourse: GSE93080, GSE98367, GSE138405, GSE206145, GSE120943
-
Cell type: RPE, Hela-Kyoto, Monocytes, GM12878, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: NIPBL,SA1,SMC1
-
CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
84% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"15_Quies": 81%,
"5_TxWk": 7%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: EGR2, ERG2, POU5F1, TRIM28, NME2, SPI1, ERG3, DDX5, ZSCAN4, SPIB, HOXB13, IKZF1, ZFHX2
- Target gene symbol (double-evidenced CRMs): SMIM11A,RUNX1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 4
- Related genes and loops