- Basic information
- CohesinDB ID: CDBP00417982
- Locus: chr21-35141178-35142738
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Data sourse: GSE138405, GSE111913, GSE206145, GSE206145-NatGen2015, ENCSR153HNT
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Cell type: RPE, Hela-Kyoto, Fibroblast, RT-112, K-562
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: SA1,Rad21,SMC1,SA2,Mau2
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
84% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 74%,
"5_TxWk": 11%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: POU2F2, CBX1, CBX3, HDAC1, EBF1, ID3, ZFX, WT1, SMAD3, STAT1, ZBTB33, KDM1A, ZNF384, MYC, RAD21, SP140, ZFP36, HIF1A, GRHL3, ATF2, PRDM9, MAX, ZNF143, GATA1, RCOR1, CDX2, ARNTL, NR3C1, CEBPB, TRIM28, ZMYM3, NR2F1, NFE2L2, EZH2, ZNF334, AR, HDAC2, RBM25, TRIM24, PTBP1, EGR1, HNRNPLL, BRD4, PHIP, BCOR, JUND, ZNF92, ADNP, ZNF316
- Target gene symbol (double-evidenced CRMs): RUNX1,SMIM11A
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 14
- Related genes and loops