- Basic information
- CohesinDB ID: CDBP00417986
- Locus: chr21-35149134-35152188
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Data sourse: GSE98367, GSE138405, GSE206145, GSE206145-NatGen2015, ENCSR000EDE, GSE116344, GSE126990, GSE108869, GSE165895
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Cell type: RPE, Hela-Kyoto, Fibroblast, RH4, HEK293T, HeLa-S3, Macrophage, HFFc6
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 8% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.911
- Subunit: NIPBL,SA1,Rad21,SMC1,SA2,Mau2,SMC3
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
84% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 68%,
"7_Enh": 15%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: GATA6, RUNX2, EZH2, BRD2, GATA1
- Target gene symbol (double-evidenced CRMs): SMIM11A,RUNX1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000205670,
ENSG00000159216,
- Related loop:
chr21:34350000-34375000~~chr21:35125000-35150000,
chr21:34350000-34375000~~chr21:35150000-35175000,
chr21:34850000-34875000~~chr21:35150000-35175000,
chr21:34875000-34900000~~chr21:35125000-35150000,
chr21:34875000-34900000~~chr21:35150000-35175000,
chr21:35050000-35075000~~chr21:35150000-35175000,
chr21:35125000-35150000~~chr21:35250000-35275000,
chr21:35125000-35150000~~chr21:35375000-35400000,
chr21:35125000-35150000~~chr21:35825000-35850000,