- Basic information
- CohesinDB ID: CDBP00417995
- Locus: chr21-35171397-35172201
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Data sourse: GSE67783, GSE86191, GSE111913, GSE206145-NatGen2015, ENCSR153HNT, GSE83726
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Cell type: Fibroblast, RH4, HCT-116, RT-112, K-562, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.933
- Subunit: SA1,Rad21,SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: non-Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
84% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 64%,
"7_Enh": 23%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, NFATC3, FOSL1, SMC1A, ZSCAN5D, MYCN, ZFX, XBP1, GTF2B, ZBTB48, WT1, STAT1, FOXA1, ERG3, ERG2, CDK9, HOXB13, ZKSCAN1, ERG, YY1, RELA, HDGF, NOTCH1, EHMT2, ATF3, RUNX2, BCL11A, SMARCA4, MCM3, SP140, GRHL3, RAD21, GATA3, GABPA, TAL1, PRDM14, CDK8, NR2F6, VDR, KLF4, JMJD1C, STAT5B, TRIM28, MYB, KLF6, ZNF26, NR2F1, MLL, NCOA1, USF2, SETDB1, EVI1, ELF3, CTCF, SPI1, E4F1, TBX21, LMO1, AR, GATA6, NR4A1, DPF2, ZBTB40, REST, ATF7, FLI1, NOTCH3, BRD4, ILF3, E2F1, MAZ, SMC3, STAG1
- Target gene symbol (double-evidenced CRMs): RUNX1,SMIM11A
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops