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Basic information

CohesinDB ID: CDBP00418001

Locus: chr21-35195081-35196351

Data sourse: ENCSR000BLY, GSE206145, GSE206145-NatGen2015, GSE135093, GSE68388, GSE165895

Cell type: RPE, Fibroblast, IMR-90, SK-N-SH, HuCC-T1, HFFc6

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 2% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.933

Subunit: NIPBL,Rad21,SMC1,SA2,Mau2,SMC3

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 84% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 60%, "5_TxWk": 15%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOSL1, FOXA2, CBX3, TOP2A, XBP1, ZSCAN16, SMAD3, FOXA1, ERG3, PBX2, SMARCC1, PRDM10, HOXC5, RELA, JUNB, ATF3, MYC, NFIC, SMARCA4, GATA4, ARID1B, RAD21, PRDM1, PBX4, DAXX, HIF1A, PROX1, RXRA, GATA3, NKX2-1, GRHL3, TAL1, CBFA2T3, PBX3, STAT3, ZNF143, IKZF1, FOS, MAX, VDR, NR3C1, TEAD1, TRIM28, KLF6, TCF7L2, NFE2L2, TP53, BRD2, JUN, TCF12, BCL11A, EP300, USF1, REST, GATA2, TRIM24, JUND, BRD4, ZNF316, FOSL2

Target gene symbol (double-evidenced CRMs): SMIM11A,RUNX1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000205670, ENSG00000159216,

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Deatailed information for cohesin site CDBP00418001