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Basic information

CohesinDB ID: CDBP00418002

Locus: chr21-35196740-35200400

Data sourse: GSE104888, ENCSR000FAD, ENCSR000BSB, ENCSR501LQA, GSE116868, ENCSR760NPX, ENCSR000BLY, ENCSR150EFU, GSE131606, GSE108869, ENCSR000BUC, GSE165895, ENCSR000EFJ, GSE67783, GSE138405, GSE76893, GSE101921, GSE135093, GSE206145-NatGen2015, GSE138105, ENCSR703TNG, GSE116344, ENCSR895JMI, ENCSR193NSH, ENCSR768DOX, GSE206145, GSE85526, ENCSR981FDC, ENCSR000BMY, ENCSR000EHX, ENCSR620NWG, ENCSR984DZW, ENCSR853VWZ, GSE110061, GSE129526, ENCSR000HPG, ENCSR676MJK, ENCSR335RKQ, ENCSR000EDE, ENCSR153HNT, GSE68388, GSE126990, ENCSR000ECS

Cell type: RH4, SLK, HuCC-T1, RPE, HMEC, Fibroblast, HEKn, HeLa-S3, IMR-90, K-562, HFFc6, DKO, MB157, GM12878, SK-N-SH, MCF-7, Hela-Kyoto, HCT-116, A-549, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 21% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.778

Subunit: NIPBL,SA1,Rad21,SMC1,SA2,Mau2,SMC3

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 84% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 44%, "5_TxWk": 23%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: AR, RUNX2, FOXA1, ZNF334, CTCF

Target gene symbol (double-evidenced CRMs): RUNX1,SETD4,SMIM11A,RCAN1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000205670, ENSG00000159200, ENSG00000159216, ENSG00000185917,

eachgene

Deatailed information for cohesin site CDBP00418002