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Basic information

CohesinDB ID: CDBP00418005

Locus: chr21-35215746-35216115

Data sourse: GSE116344, GSE206145-NatGen2015, ENCSR153HNT

Cell type: K-562, Fibroblast, RH4

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.967

Subunit: Mau2,SA1,Rad21,SA2

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 84% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 56%, "5_TxWk": 23%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: MBD3, FOXO1, FOSL1, PGR, ZNF660, SOX2, XBP1, FOXA1, PBX2, TFAP4, MEN1, ATF3, ZC3H8, CHD7, ATF4, SMARCE1, TP63, MITF, CDX2, MAF, KLF5, TEAD1, ELF1, KLF6, SNAI2, ZNF217, ESR1, HNF1B, HDAC8, USF2, CTCF, JUN, TCF12, BAF155, EP300, MNT, GATA6, PYGO2, DPF2, IRF4, RFX5, TRIM24, SOX6, DEK, RAD51, DDX20, SMC1, TEAD4, ZNF175, EHMT2, TFAP2C, ID3, CTBP1, ZSCAN21, ZBTB17, STAT1, ZNF205, DDX5, ZNF300, ERG, HOXC5, PAX6, MYC, SMARCA4, ARID1B, RAD21, GRHL3, PROX1, NKX2-1, RXRA, GABPA, STAT3, APC, NKX3-1, RCOR1, ZNF639, ARNTL, NR3C1, ZNF750, CEBPB, ESRRA, CREB1, KLF8, GRHL2, FEZF1, TRPS1, ZHX2, EHF, IRF1, HDAC2, GATA2, GATAD2B, SIX2, NR2C2, SMARCA5, NCOA2, RUNX1, CBX1, SMC1A, MAFG, NKX2-2, AFF4, ZFX, SIN3A, SMAD3, SMARCC1, TWIST1, PRDM10, CREBBP, ZXDC, RUNX2, CDK6, GATA4, GR, ARNT, PBX4, DAXX, ATF2, ZEB2, FOXM1, PBX3, FOS, CDK8, MED1, ZNF584, ZEB1, MYB, SCRT2, PIAS1, NR1H2, C11orf30, L3MBTL2, NCOA1, ZNF41, MAFK, NIPBL, SP1, TFAP2A, HNF4A, ARID1A, ZHX1, ATF7, ASH2L, CTBP2, PHIP, MBD2, FOXP1, SMC3, ELL2, STAG1, STAG2, FOXA2, CBX3, CHD2, PAF1, MAFF, ESR2, CDK9, HOXB13, ZNF589, ZNF19, KDM1A, RELA, TARDBP, NEUROD1, AHR, JUNB, HIF1A, GATA3, MGA, MAX, NRIP1, ZNF143, MTA1, GATA1, KLF4, ZNF592, CEBPG, NCOA3, NR2F2, SP7, TCF7L2, NR2F1, KDM5B, TP53, ZNF687, PKNOX1, NFKB1, MYOD1, PHOX2B, ELF3, BRD2, T, BHLHE40, AR, ZNF579, ZBTB40, YAP1, EGLN2, RNF2, NOTCH3, BRD4, JUND, CLOCK, CUX1, ZNF24, ZNF316, FOSL2

Target gene symbol (double-evidenced CRMs): SETD4,SMIM11A,RUNX1,RCAN1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000205670, ENSG00000159200, ENSG00000159216, ENSG00000185917,

eachgene

Deatailed information for cohesin site CDBP00418005