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Basic information

CohesinDB ID: CDBP00418008

Locus: chr21-35225613-35229873

Data sourse: ENCSR000BLD, ENCSR230ZWH, GSE72082, ENCSR000BSB, ENCSR000BLY, GSE105028, GSE131606, GSE108869, GSE25021, ENCSR917QNE, ENCSR000EFJ, GSE165895, GSE93080, GSE67783, ENCSR000BKV, GSE138405, GSE206145-NatGen2015, GSE112028, GSE138105, ENCSR703TNG, GSE116344, ENCSR879KXD, ENCSR000EHW, GSE206145, GSE62063, ENCSR000BMY, ENCSR635OSG, ENCSR000BTQ, ENCSR167MTG, GSE129526, ENCSR000HPG, GSE111913, GSE155324, ENCSR054FKH, ENCSR000EDE, ENCSR153HNT, GSE68388, GSE83726, GSE126990, GSE50893, ENCSR000ECS

Cell type: RH4, GM10847, GM2610, SLK, GM19240, HSPC, Liver, HuCC-T1, H9-hESC, B-cell, GM2630, RPE, Fibroblast, GM12890, HeLa-S3, GM2255, IMR-90, K-562, GM18486, HFFc6, H1-hESC, SNYDER, GM18505, Lymphoblast, GM12878, GM12891, GM2588, SK-N-SH, GM19239, HeLa-Tet-On, RT-112, Ramos, MCF-7, GM12892, Hela-Kyoto, HCT-116, Hep-G2, GM18951

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 22% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.578

Subunit: NIPBL,SA1,Rad21,SMC1,SA2,Mau2,SMC3

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 84% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "7_Enh": 33%, "15_Quies": 28%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOXO1, CBFA2T2, MEF2B, PGR, HDAC1, NKX2-2, FOXA2, EBF1, ID3, MEIS2, MTA2, FOXA1, FOXF1, ERG3, PBX2, HOXB13, MEF2A, CREBBP, ZNF274, SMARCA4, ARID1B, ZNF184, GRHL3, PROX1, RXRA, GATA3, HMBOX1, TAL1, CBFA2T3, MAFB, NKX3-1, GATA1, PBX3, STAT3, IKZF1, HAND2, NR2F6, CDX2, PDX1, PML, NR2F2, KMT2A, CEBPD, NR2F1, TRIM28, ESR1, PKNOX1, C11orf30, STAT5A, KLF16, PHOX2B, TCF12, MAFK, BCL11A, EP300, BAF155, SP1, AR, DPF2, ZBTB40, GATA2, TRIM24, SOX6, NCOR1, BRD4, PHIP, JUND, FOXP1, TEAD4, MEF2D, ADNP, FOSL2

Target gene symbol (double-evidenced CRMs): SMIM11A,RUNX1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000205670, ENSG00000159216,

eachgene

Deatailed information for cohesin site CDBP00418008