- Basic information
- CohesinDB ID: CDBP00418011
- Locus: chr21-35235747-35236728
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Data sourse: GSE93080, GSE206145, GSE62063, ENCSR000BMY, ENCSR153HNT, GSE120943, GSE50893
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Cell type: GM12892, SNYDER, Monocytes, GM18505, GM2610, GM12878, Ramos, GM12891, GM2588, K-562, B-cell
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 3% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.878
- Subunit: NIPBL,SA1,Rad21,SMC1,Mau2
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
84% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 54%,
"9_Het": 20%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, CBX5, SMC1A, MEF2B, POU2F2, MTA3, EBF1, GTF2B, DUX4, STAT1, MEF2C, DDX5, CDK9, YY1, RELA, NOTCH1, JUNB, MYC, RUNX3, RAD21, TCF4, BHLHE22, ATF2, BATF, GABPA, STAT3, MAX, ETV6, SPIB, PAX5, CDK8, ZNF143, JMJD1C, TRIM28, BCLAF1, MYB, OCA2, NFKB1, ZFP91, CTCF, TCF12, SPI1, EP300, NIPBL, BCL11A, TBX21, NR4A1, SP1, REST, TRIM24, IRF4, BRD4, TCF3, ZNF24, MLLT1, RBPJ
- Target gene symbol (double-evidenced CRMs): SMIM11A,RUNX1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops