- Basic information
- CohesinDB ID: CDBP00418012
- Locus: chr21-35239418-35240383
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Data sourse: GSE67783, ENCSR000BLY, ENCSR879KXD, GSE206145-NatGen2015, GSE83726, GSE130135, GSE116344
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Cell type: Fibroblast, RH4, HEK293T, SK-N-SH, K-562, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.933
- Subunit: Mau2,SA1,Rad21
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
84% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 48%,
"7_Enh": 18%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: ZNF660, SOX2, XBP1, PATZ1, ZBTB44, CHD7, IKZF3, MZF1, MAF, ZNF629, MYOG, ZNF121, TRIM28, KLF10, CTCF, EP300, TRIM24, ZNF423, GLIS1, POU2F2, POU5F1, MYCN, TOP2A, ZBTB17, ZBTB48, ERG2, PBX1, ASCL1, MYC, SMARCA4, RAD21, STAT3, NFE2, ZNF639, CEBPB, KMT2A, EZH2, FEZF1, EBF3, FLI1, MRTFB, MYF5, RUNX1, MAFG, EZH2phosphoT487, ZNF335, ZFX, POU4F2, ERG3, ZNF549, ZNF384, ZNF35, ZNF133, RUNX2, GATA4, OSR2, ZNF184, ATF2, ZEB2, MED1, ZBTB18, KLF9, USF1, REST, POU2F3, PHIP, TCF3, STAG1, ZNF394, CBFA2T2, FOXA2, EBF1, ZNF600, ZNF692, WT1, KDM1A, RELA, ZIC2, HIF1A, MAX, HAND2, CEBPG, SP7, MYOD1, BRD2, AR, PAX3-FOXO1, ZBTB42, ZNF366, RNF2, NOTCH3, BRD4, SCRT1, MAZ, FOSL2
- Target gene symbol (double-evidenced CRMs): SMIM11A,RUNX1
- Function elements
- Human SNPs: Refractive_error
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops