- Basic information
- CohesinDB ID: CDBP00418013
- Locus: chr21-35243153-35243584
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Data sourse: ENCSR000BTQ, GSE206145-GSE177045, GSE72082, GSE68388, ENCSR703TNG, GSE25021
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Cell type: MCF-7, HuCC-T1
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 3% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: Mau2,Rad21,SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
84% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 69%,
"14_ReprPCWk": 18%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: PGR, CBX1, SIN3A, CTBP1, GTF2B, SMAD3, FOXA1, PBX2, HOXB13, ERG, ZXDC, CREBBP, ATF3, RUNX2, GR, RAD21, PBX4, HIF1A, ARNT, GATA3, SMARCE1, STAT3, NRIP1, FOS, RCOR1, ZNF750, CEBPB, ESRRA, NR3C1, TEAD1, TRIM28, NR2F2, TFAP2C, ZNF217, ESR1, PKNOX1, TP53, GRHL2, PHOX2B, JUN, TCF12, BAF155, EP300, AR, DPF2, ZNF579, HDAC2, GATA2, BRD4, CTBP2, MBD2, JUND, CUX1, TEAD4, AHR, FOSL2
- Target gene symbol (double-evidenced CRMs): SMIM11A,RUNX1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops