- Basic information
- CohesinDB ID: CDBP00418014
- Locus: chr21-35244019-35244879
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Data sourse: ENCSR230ZWH, GSE67783, GSE86191, ENCSR000HPG, GSE111913, GSE206145-NatGen2015, ENCSR000EDE, GSE68388, GSE108869, ENCSR000ECS, ENCSR917QNE
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Cell type: Fibroblast, HCT-116, HeLa-S3, IMR-90, RT-112, Liver, HSPC, HuCC-T1
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.911
- Subunit: SA1,Rad21,SMC1,SA2,Mau2,SMC3
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: False
- Compartment:
84% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 64%,
"14_ReprPCWk": 17%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, CTNNB1, CHD8, PGR, CEBPA, FOXA2, CHD2, MEIS2, SMAD3, FOXA1, HLF, FOXF1, HOXB13, TBP, ERG, YY1, RELA, JUNB, RUNX2, SMARCA4, GR, RAD21, PBX4, RXRA, GABPA, MECOM, STAT3, MAX, NRIP1, FOS, CDK8, RCOR1, MED1, ZNF750, CEBPB, JMJD1C, NR3C1, MYB, SCRT2, ESR1, OCA2, NFKB1, CTCF, JUN, SPI1, BCL11A, SP1, HNF4A, EP300, BAF155, AR, TRIM24, RFX5, DEK, HSF1, NOTCH3, BRD4, SCRT1, NFIL3, SMC3, STAG1, TFAP2C
- Target gene symbol (double-evidenced CRMs): RUNX1,SMIM11A
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops