- Basic information
- CohesinDB ID: CDBP00418018
- Locus: chr21-35261735-35262939
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Data sourse: ENCSR000BTQ, GSE206145-GSE177045, GSE72082, GSE138405, GSE76893, ENCSR703TNG, GSE25021
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Cell type: MCF-7, Hela-Kyoto
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 4% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: NIPBL,SA1,Rad21,SMC1,SA2,Mau2
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
81% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 84%,
"5_TxWk": 9%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: MBD3, FOSL1, PGR, SMC1A, CBFA2T2, HDAC1, FOXA2, SIN3A, MEIS2, CTBP1, TEAD4, DUX4, ESR2, FOXA1, RELA, CREBBP, ZXDC, ATF3, GATA4, ARID1B, RAD21, ARNT, GRHL3, NKX2-1, ATF2, GATA3, SMARCE1, FOXM1, CBFA2T3, NRIP1, FOS, TAL1, RCOR1, HAND2, MED1, NR3C1, ESRRA, NCOA3, NR2F2, TEAD1, CREB1, NR2F1, TFAP2C, ZNF217, ESR1, PITX3, GRHL2, PHOX2B, JUN, TCF12, EP300, NIPBL, AR, DPF2, GATAD2B, JUND, CTBP2, MBD2, BRD4, CUX1, HEXIM1-CDK9, NCOA2, ZNF24, STAG1, AHR, FOSL2
- Target gene symbol (double-evidenced CRMs): SMIM11A,RUNX1,SETD4
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000205670,
ENSG00000159216,
ENSG00000185917,
- Related loop:
chr21:34350000-34375000~~chr21:35250000-35275000,
chr21:34875000-34900000~~chr21:35250000-35275000,
chr21:34887508-34892091~~chr21:35255866-35258344,
chr21:35050000-35075000~~chr21:35250000-35275000,
chr21:35050353-35052253~~chr21:35255866-35258344,
chr21:35125000-35150000~~chr21:35250000-35275000,
chr21:35204316-35206905~~chr21:35255864-35258282,
chr21:35250000-35275000~~chr21:35375000-35400000,
chr21:35250000-35275000~~chr21:35500000-35525000,
chr21:35250000-35275000~~chr21:35550000-35575000,
chr21:35250000-35275000~~chr21:35575000-35600000,
chr21:35250000-35275000~~chr21:35825000-35850000,
chr21:35250000-35275000~~chr21:35925000-35950000,
chr21:35250000-35275000~~chr21:36025000-36050000,