- Basic information
- CohesinDB ID: CDBP00418020
- Locus: chr21-35268268-35268825
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Data sourse: GSE206145, GSE206145-NatGen2015
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Cell type: RPE, Fibroblast
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: Mau2,NIPBL,Rad21
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
81% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 85%,
"14_ReprPCWk": 8%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, POU2F2, SMC1A, MEIS1, AFF4, TOP2A, XBP1, GTF2B, DUX4, ZNF134, CDK9, ZNF300, KDM1A, ERG, RELA, MYC, MCM3, GRHL3, HIF1A, ARNT, PRDM9, SATB1, FOXM1, TP63, ZNF10, ETV6, RCOR1, TERF1, TRIM28, ZMYM3, EZH2, OCA2, CTCF, SPI1, AR, IRF1, RBM25, ZNF528
- Target gene symbol (double-evidenced CRMs): SMIM11A,RUNX1,SETD4
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000205670,
ENSG00000159216,
ENSG00000185917,
- Related loop:
chr21:34350000-34375000~~chr21:35250000-35275000,
chr21:34875000-34900000~~chr21:35250000-35275000,
chr21:35050000-35075000~~chr21:35250000-35275000,
chr21:35125000-35150000~~chr21:35250000-35275000,
chr21:35250000-35275000~~chr21:35375000-35400000,
chr21:35250000-35275000~~chr21:35500000-35525000,
chr21:35250000-35275000~~chr21:35550000-35575000,
chr21:35250000-35275000~~chr21:35575000-35600000,
chr21:35250000-35275000~~chr21:35825000-35850000,
chr21:35250000-35275000~~chr21:35925000-35950000,
chr21:35250000-35275000~~chr21:36025000-36050000,