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Basic information

CohesinDB ID: CDBP00418021

Locus: chr21-35273218-35273904

Data sourse: ENCSR000BLD, ENCSR000BTQ, GSE206145-GSE177045, GSE72082, ENCSR703TNG, GSE111913, GSE76893, GSE68388, GSE83726, GSE116344, GSE25021

Cell type: MCF-7, H1-hESC, RH4, RT-112, HuCC-T1

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 7% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.944

Subunit: SA1,Rad21,SMC1,SA2,Mau2

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 81% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 77%, "7_Enh": 10%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOSL1, PGR, SOX2, NME2, XBP1, FOXA1, PBX2, NFIC, SMARCE1, CDX2, MYOG, KLF5, TEAD1, TRIM28, KLF6, SMAD5, ZNF217, OCA2, ESR1, LMO2, HNF1B, CTCF, TCF12, JUN, BAF155, EP300, GATA6, DPF2, IRF4, ZNF528, TEAD4, TFAP2C, RBPJ, POU2F2, CDK9-HEXIM1, POU5F1, CTBP1, STAT1, ZNF205, ERG, HOXC5, EZH1, MYC, SMARCA4, RAD21, LHX2, GRHL3, PROX1, NKX2-1, RXRA, STAT3, SOX10, NKX3-1, ARNTL, ZNF750, CEBPB, NR3C1, ESRRA, EZH2, GRHL2, TRPS1, IRF1, HDAC2, GATA2, GATAD2B, NCOA2, RUNX1, CBX1, SMC1A, CEBPA, ZBTB24, SIN3A, ZFX, SMAD3, ZXDC, CREBBP, RUNX2, GATA4, ARNT, PBX4, PBX3, FOXM1, CDK8, MED1, ZEB1, PML, TERF1, PIAS1, ZMYM3, TAF7, KLF9, SETDB1, NIPBL, TFAP2A, SP1, HNF4A, REST, ASH2L, PHIP, MBD2, SMC3, STAG1, ZNF283, PPARG, FOXA2, ZNF316, GTF2B, HOXB13, ZKSCAN1, KDM1A, YY1, RELA, HIF1A, GATA3, MAX, NRIP1, ZNF143, TLE3, KLF4, NR2F2, TCF7L2, KDM5B, TP53, ZBTB6, PKNOX1, ZNF334, ELF3, BRD2, AR, RXR, EGLN2, ZBTB26, NCOR1, NOTCH3, BRD4, JUND, AHR, FOSL2

Target gene symbol (double-evidenced CRMs): SMIM11A,SETD4,RUNX1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000205670, ENSG00000159216, ENSG00000185917,

eachgene

Deatailed information for cohesin site CDBP00418021