- Basic information
- CohesinDB ID: CDBP00418022
- Locus: chr21-35274166-35275146
-
Data sourse: GSE116344, ENCSR153HNT, GSE68388
-
Cell type: K-562, RH4, HuCC-T1
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SA1,Rad21,SMC1
-
CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
81% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"15_Quies": 72%,
"7_Enh": 15%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: FOSL1, PGR, SOX2, NME2, XBP1, FOXA1, PBX2, NFIC, SMARCE1, CDX2, MYOG, KLF5, TEAD1, TRIM28, KLF6, SMAD5, ZNF217, OCA2, ESR1, LMO2, HNF1B, CTCF, TCF12, JUN, BAF155, EP300, GATA6, DPF2, IRF4, ZNF528, TEAD4, TFAP2C, RBPJ, POU2F2, CDK9-HEXIM1, POU5F1, CTBP1, STAT1, ZNF205, ERG, HOXC5, EZH1, MYC, SMARCA4, RAD21, LHX2, GRHL3, PROX1, NKX2-1, RXRA, STAT3, SOX10, NKX3-1, ARNTL, ZNF750, CEBPB, NR3C1, ESRRA, EZH2, GRHL2, TRPS1, IRF1, HDAC2, GATA2, GATAD2B, NCOA2, RUNX1, CBX1, SMC1A, CEBPA, ZBTB24, SIN3A, ZFX, SMAD3, ZXDC, CREBBP, RUNX2, GATA4, ARNT, PBX4, PBX3, FOXM1, CDK8, MED1, ZEB1, PML, TERF1, PIAS1, ZMYM3, TAF7, KLF9, SETDB1, NIPBL, TFAP2A, SP1, HNF4A, REST, ASH2L, PHIP, MBD2, SMC3, STAG1, ZNF283, PPARG, FOXA2, ZNF316, GTF2B, HOXB13, ZKSCAN1, KDM1A, YY1, RELA, HIF1A, GATA3, MAX, NRIP1, ZNF143, TLE3, KLF4, NR2F2, TCF7L2, KDM5B, TP53, ZBTB6, PKNOX1, ZNF334, ELF3, BRD2, AR, RXR, EGLN2, ZBTB26, NCOR1, NOTCH3, BRD4, JUND, AHR, FOSL2
- Target gene symbol (double-evidenced CRMs): RUNX1,SMIM11A,SETD4
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000205670,
ENSG00000159216,
ENSG00000185917,
- Related loop:
chr21:34350000-34375000~~chr21:35250000-35275000,
chr21:34350000-34375000~~chr21:35275000-35300000,
chr21:34875000-34900000~~chr21:35250000-35275000,
chr21:35050000-35075000~~chr21:35250000-35275000,
chr21:35125000-35150000~~chr21:35250000-35275000,
chr21:35250000-35275000~~chr21:35375000-35400000,
chr21:35250000-35275000~~chr21:35500000-35525000,
chr21:35250000-35275000~~chr21:35550000-35575000,
chr21:35250000-35275000~~chr21:35575000-35600000,
chr21:35250000-35275000~~chr21:35825000-35850000,
chr21:35250000-35275000~~chr21:35925000-35950000,
chr21:35250000-35275000~~chr21:36025000-36050000,
chr21:35275000-35300000~~chr21:35375000-35400000,