- Basic information
- CohesinDB ID: CDBP00418040
- Locus: chr21-35302008-35304221
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Data sourse: ENCSR230ZWH, ENCSR000BSB, ENCSR501LQA, ENCSR000BLY, ENCSR150EFU, ENCSR000ECS, GSE131606, ENCSR330ELC, GSE108869, ENCSR000BUC, GSE165895, ENCSR000EFJ, GSE138405, GSE76893, GSE101921, GSE206145-NatGen2015, GSE138105, GSE94872, ENCSR895JMI, ENCSR193NSH, GSE206145, GSE85526, ENCSR981FDC, ENCSR000EHX, ENCSR620NWG, ENCSR767DFK, ENCSR495WGO, ENCSR984DZW, ENCSR217ELF, ENCSR853VWZ, ENCSR956LGB, GSE129526, ENCSR000HPG, ENCSR676MJK, ENCSR335RKQ, ENCSR000EDE, GSE68388, GSE126990, ENCSR748MVX
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Cell type: RPE, Fibroblast, HCT-116, Hela-Kyoto, HEKn, SLK, A-549, HUVEC, HCAEC, HeLa-S3, IMR-90, SK-N-SH, Liver, HFFc6, HuCC-T1, DKO
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 16% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.822
- Subunit: NIPBL,SA1,Rad21,SMC1,SA2,Mau2,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: non-Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
81% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 68%,
"7_Enh": 10%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: PHOX2B, ZNF384, FOXA1
- Target gene symbol (double-evidenced CRMs): SMIM11A,RUNX1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops