- Basic information
- CohesinDB ID: CDBP00418056
- Locus: chr21-35336854-35337807
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Data sourse: ENCSR000BLD, GSE72082, ENCSR000BSB, ENCSR000BLY, GSE105028, GSE25021, GSE131606, GSE67783, ENCSR000BKV, GSE86191, GSE101921, GSE120943, GSE116344, GSE94872, ENCSR000BLS, GSE206145, ENCSR000ECE, GSE97394, ENCSR167MTG, GSE129526, ENCSR054FKH, ENCSR153HNT, GSE83726, GSE50893
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Cell type: RPE, H1-hESC, HCT-116, Monocytes, Hep-G2, RH4, GM19240, HUVEC, HCAEC, DKO, GM12890, HUES64, SK-N-SH, K-562, HSPC, H9-hESC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 8% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.822
- Subunit: SA1,Rad21,SA2,SMC1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
81% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 76%,
"14_ReprPCWk": 16%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOSL1, MEIS2, PBX2, ATF3, NFIC, THAP1, SMARCE1, MAF, TRIM28, NFE2L2, ESR1, CTCF, TCF12, JUN, EP300, DPF2, TRIM24, SOX6, DDX20, SMC1, TEAD4, ZNF317, MTA2, DUX4, STAT1, ARID3A, ERG, SMARCA4, ARID1B, RAD21, GRHL3, NKX2-1, GABPA, STAT3, NFE2, RCOR1, CEBPB, HDAC2, GATA2, NCOA2, ZIM3, MAFG, CEBPA, LDB1, ZFX, SMAD3, ZBTB2, RUNX2, GATA4, ARNT, ZEB2, CBFA2T3, FOS, MED1, GMEB1, PML, CEBPD, C11orf30, STAT5A, KLF16, MAFK, BCL11A, REST, STAG2, STAG1, CBFA2T2, CBX3, MTA3, CREM, FOXA2, MAFF, WT1, ZBTB33, RELA, JUNB, HIF1A, TAL1, MAX, GATA1, CEBPG, NCOA3, NR2F2, NR2F1, PKNOX1, ZNF334, MYOD1, AR, MYNN, RNF2, NCOR1, BRD4, JUND, ZNF316
- Target gene symbol (double-evidenced CRMs): SMIM11A
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000205670,
- Related loop:
chr21:34350000-34375000~~chr21:35325000-35350000,
chr21:34889215-34891491~~chr21:35339729-35341143,
chr21:35050018-35052259~~chr21:35339447-35341148,
chr21:35050056-35052270~~chr21:35339729-35341143,
chr21:35050370-35052249~~chr21:35339746-35341172,
chr21:35050423-35052303~~chr21:35339770-35341171,
chr21:35050481-35052295~~chr21:35339683-35341161,
chr21:35050528-35052327~~chr21:35339764-35341191,
chr21:35226847-35228785~~chr21:35339309-35341219,