- Basic information
- CohesinDB ID: CDBP00418057
- Locus: chr21-35340030-35340869
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Data sourse: ENCSR000BLD, GSE206145-GSE177045, GSE104888, ENCSR230ZWH, GSE72082, ENCSR000BSB, GSE116868, ENCSR000EGW, ENCSR000BLY, GSE105028, GSE121355, GSE131606, GSE108869, ENCSR000EDW, GSE25021, ENCSR917QNE, ENCSR000BKV, GSE86191, GSE138405, GSE76893, GSE206145-NatGen2015, GSE120943, GSE112028, GSE138105, ENCSR199XBQ, ENCSR703TNG, GSE106870, GSE116344, GSE94872, ENCSR000EEG, ENCSR000BLS, ENCSR000ECE, ENCSR247LSH, ENCSR000EHX, ENCSR620NWG, ENCSR748MVX, ENCSR767DFK, ENCSR217ELF, ENCSR000BTQ, GSE105004, ENCSR167MTG, ENCSR853VWZ, GSE110061, GSE129526, GSE111913, ENCSR335RKQ, ENCSR054FKH, ENCSR000EDE, ENCSR153HNT, GSE68388, GSE83726, GSE126990, GSE50893, ENCSR000ECS, GSE38411
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Cell type: RH4, SLK, GM19240, CVI-hiPSC, Liver, HuCC-T1, H9-hESC, GM2630, Fibroblast, GM12890, HeLa-S3, GM2255, BCBL-1, K-562, GM18486, DKO, GM18526, H1-hESC, SNYDER, Monocytes, MB157, GM12878, GM2588, SK-N-SH, GM19239, HeLa-Tet-On, RT-112, GM19099, MCF-7, GM12892, Hela-Kyoto, HCT-116, Hep-G2, A-549, HUVEC, GM19238, HeLa
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 25% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.589
- Subunit: SA1,Rad21,SMC1,SA2,Mau2,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
81% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 76%,
"14_ReprPCWk": 19%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: POU2F2, RAD21, ARNT, STAT3, SPI1
- Target gene symbol (double-evidenced CRMs): SMIM11A,RUNX1
- Function elements
- Human SNPs: Juvenile_idiopathic_arthritis_(oligoarticular_or_rheumatoid_factor-negative_polyarticular)
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000205670,
ENSG00000159216,
- Related loop:
chr21:34350000-34375000~~chr21:35325000-35350000,
chr21:34889215-34891491~~chr21:35339729-35341143,
chr21:35050018-35052259~~chr21:35339447-35341148,
chr21:35050056-35052270~~chr21:35339729-35341143,
chr21:35050370-35052249~~chr21:35339746-35341172,
chr21:35050423-35052303~~chr21:35339770-35341171,
chr21:35050481-35052295~~chr21:35339683-35341161,
chr21:35050528-35052327~~chr21:35339764-35341191,
chr21:35226847-35228785~~chr21:35339309-35341219,