- Basic information
- CohesinDB ID: CDBP00418059
- Locus: chr21-35345314-35345950
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Data sourse: GSE206145-NatGen2015, GSE67783, GSE86191
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Cell type: Fibroblast, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SA1,Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
81% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 65%,
"14_ReprPCWk": 21%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, FOXO1, CBFA2T2, BCL6, MAFG, ZSCAN5D, TOP2A, ID3, ZFX, ZNF534, MEIS2, TEAD4, CTBP1, ZSCAN5A, SIN3A, ERG2, PBX2, TWIST1, PRDM10, HNRNPK, YY1, HDGF, EHMT2, SMARCA4, ARID1B, PBX4, ARNT, GATA3, PRDM9, ZEB2, GABPA, TAL1, PBX3, CBFA2T3, ZNF10, FOXM1, IKZF1, NFE2, LEF1, RCOR1, GATA1, MAX, ZNF750, ZNF592, ZNF506, NR2F2, ELF1, ZMYM3, EZH2, LMO2, C11orf30, ZSCAN22, EGR2, TCF12, ELF4, EP300, E4F1, LMO1, DPF2, ZBTB40, GATA2, ZBTB7A, RBM25, TRIM24, RNF2, NCOR1, JUND, E2F1, MAZ, ZNF350, SMC3, ZNF24, STAG1, ZNF316
- Target gene symbol (double-evidenced CRMs): SMIM11A
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000205670,
- Related loop:
chr21:34350000-34375000~~chr21:35325000-35350000,
chr21:34350000-34375000~~chr21:35350000-35375000,
chr21:34775000-34800000~~chr21:35350000-35375000,
chr21:34875000-34900000~~chr21:35350000-35375000,
chr21:34889215-34891491~~chr21:35339729-35341143,
chr21:35050018-35052259~~chr21:35339447-35341148,
chr21:35050056-35052270~~chr21:35339729-35341143,
chr21:35050370-35052249~~chr21:35339746-35341172,
chr21:35050423-35052303~~chr21:35339770-35341171,
chr21:35050481-35052295~~chr21:35339683-35341161,
chr21:35050528-35052327~~chr21:35339764-35341191,
chr21:35225000-35250000~~chr21:35350000-35375000,
chr21:35226847-35228785~~chr21:35339309-35341219,
chr21:35350000-35375000~~chr21:35825000-35850000,