- Basic information
- CohesinDB ID: CDBP00418063
- Locus: chr21-35359135-35359624
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Data sourse: GSE206145-NatGen2015, GSE206145-GSE177045
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Cell type: MCF-7, Fibroblast
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: Mau2
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
81% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 81%,
"14_ReprPCWk": 10%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, NELFA, PGR, CBX1, CREM, CTBP1, SMAD3, FOXA1, MEF2C, KDM1A, RELA, CREBBP, JUNB, AHR, RUNX2, MYC, NFIC, GR, RUNX3, ARNT, HIF1A, PBX4, GATA3, BATF3, GABPA, BATF, STAT3, ATF2, TP63, NRIP1, SPIB, CDK8, RCOR1, BACH2, MED1, ZNF750, ESRRA, KLF4, NCOA3, TEAD1, NR3C1, STAT5B, CEBPB, TCF7L2, CREB1, KDM5B, SMAD5, ESR1, OCA2, PKNOX1, MLL, GRHL2, TRPS1, STAT5A, PHOX2B, EP300, TFAP2A, SPI1, TBX21, AR, BCL11A, YAP1, GATA2, EGLN2, HOXA9, BRD4, CTBP2, JUND, TEAD4, STAG1, TFAP2C, EED
- Target gene symbol (double-evidenced CRMs): SMIM11A,RUNX1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops