- Basic information
- CohesinDB ID: CDBP00418064
- Locus: chr21-35359855-35361915
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Data sourse: GSE206145-GSE177045, GSE72082, GSE98367, GSE138405, GSE206145, GSE120943, GSE83726, ENCSR703TNG, GSE25021
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Cell type: MCF-7, RPE, Hela-Kyoto, RH4, Monocytes, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 5% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.933
- Subunit: NIPBL,SA1,Rad21,SMC1,SA2,Mau2
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
81% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 70%,
"5_TxWk": 10%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: PGR, TOP2A, SOX2, FOXA1, SUZ12, ZNF596, ZNF300, KDM1A, RELA, MYC, GR, ARNT, HIF1A, MITF, MED1, NR3C1, ESRRA, TEAD1, LMO2, ESR1, PAX3-FOXO1, AR, POU2F3, HSF1, BRD4, SMC3, TFAP2C
- Target gene symbol (double-evidenced CRMs): SMIM11A,RUNX1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops