- Basic information
- CohesinDB ID: CDBP00418067
- Locus: chr21-35366084-35367938
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Data sourse: ENCSR000BTQ, GSE72082, GSE206145, GSE206145-NatGen2015, GSE62063, ENCSR703TNG, GSE25021, GSE116344
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Cell type: MCF-7, RPE, Fibroblast, RH4, Ramos
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 6% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: NIPBL,SA1,Rad21,SA2,Mau2
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
81% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 68%,
"7_Enh": 18%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOSL1, PGR, SOX2, XBP1, FOXA1, ATF3, ZFP64, ZBTB44, CHD7, SMARCE1, ZNF320, MYOG, KLF6, NFE2L2, ZNF217, ESR1, OCA2, JUN, TCF12, CTCF, BAF155, GATA6, DPF2, SMC1, TFAP2C, NANOG, POU5F1, TOP2A, ID3, CTBP1, DUX4, ERG, ASCL1, ETS1, MYC, RAD21, GRHL3, NKX2-1, GABPA, STAT3, IKZF1, NFE2, RCOR1, NR3C1, CEBPB, GRHL2, HDAC2, GATA2, SIX2, RUNX1, CBX1, SMC1A, MAFG, SMAD3, ERG3, ZXDC, CREBBP, RUNX2, GATA4, PBX4, ARNT, FOS, MED1, C11orf30, NUP98-HOXA9, REST, ASH2L, MBD2, SMC3, STAG2, STAG1, PPARG, FOXA2, EBF1, MAFF, HOXB13, RELA, JUNB, AHR, HIF1A, GATA3, MAX, NRIP1, GATA1, CEBPG, KLF4, KDM5B, MYOD1, AR, HSF1, BRD4, JUND, NR1H3, ZNF316
- Target gene symbol (double-evidenced CRMs): SMIM11A,RUNX1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 2
- Related genes and loops