- Basic information
- CohesinDB ID: CDBP00418069
- Locus: chr21-35371312-35371875
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Data sourse: ENCSR000BLD, GSE206145-GSE177045
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Cell type: MCF-7, H1-hESC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 0% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: Mau2,Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
81% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 86%,
"5_TxWk": 6%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: PGR, POU2F2, FOXA2, POU5F1, NKX2-2, CEBPA, XBP1, FOXA1, ZNF205, ERG3, ZNF485, ERG2, CDK9, KDM1A, ZNF19, RELA, YY1, ZNF384, CREBBP, GATA4, PRDM1, DAXX, ARNT, HIF1A, PROX1, GRHL3, GATA3, TAL1, PAX5, NRIP1, RCOR1, ARNTL, CEBPG, CEBPB, NCOA3, ZMYM3, EZH2, TP53, ESR1, EGR2, CTCF, AR, GATA2, RBM25, SIX2, BRD4, BCOR, ZNF24
- Target gene symbol (double-evidenced CRMs): SMIM11A,RUNX1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 2
- Related genes and loops
- Related gene:
ENSG00000205670,
ENSG00000159216,
- Related loop:
chr21:34350000-34375000~~chr21:35350000-35375000,
chr21:34700000-34725000~~chr21:35375000-35400000,
chr21:34775000-34800000~~chr21:35350000-35375000,
chr21:34850000-34875000~~chr21:35375000-35400000,
chr21:34875000-34900000~~chr21:35350000-35375000,
chr21:34875000-34900000~~chr21:35375000-35400000,
chr21:34889215-34891491~~chr21:35367866-35369303,
chr21:34889251-34892128~~chr21:35374172-35375997,
chr21:34900000-34925000~~chr21:35375000-35400000,
chr21:35025000-35050000~~chr21:35375000-35400000,
chr21:35050000-35075000~~chr21:35375000-35400000,
chr21:35050390-35052342~~chr21:35374616-35376147,
chr21:35125000-35150000~~chr21:35375000-35400000,
chr21:35200000-35225000~~chr21:35375000-35400000,
chr21:35225000-35250000~~chr21:35350000-35375000,
chr21:35250000-35275000~~chr21:35375000-35400000,
chr21:35275000-35300000~~chr21:35375000-35400000,
chr21:35350000-35375000~~chr21:35825000-35850000,
chr21:35375000-35400000~~chr21:35825000-35850000,