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Basic information

CohesinDB ID: CDBP00418071

Locus: chr21-35373259-35373669

Data sourse: GSE116344, GSE206145-NatGen2015, ENCSR153HNT

Cell type: K-562, Fibroblast, RH4

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.967

Subunit: Mau2,SA1,Rad21

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 81% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 87%, "5_TxWk": 5%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RELA, CBFA2T3, CBFA2T2, CHD8, MYC, EBF1, TOP2A, MEIS2, XBP1, HIF1A, SOX11, DUX4, TAL1, PHOX2B, PBX2, CDK8

Target gene symbol (double-evidenced CRMs): RUNX1,SMIM11A

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000205670, ENSG00000159216,

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Deatailed information for cohesin site CDBP00418071