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Basic information

CohesinDB ID: CDBP00418074

Locus: chr21-35381568-35382502

Data sourse: ENCSR000BTQ, GSE206145-GSE177045, GSE72082, GSE86191, GSE206145, ENCSR703TNG, GSE116344

Cell type: MCF-7, RH4, HCT-116, RPE

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 3% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.956

Subunit: Mau2,Rad21

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 81% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 88%, "14_ReprPCWk": 5%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: SMC1A, FOXA2, NKX2-2, SIN3A, GTF2B, SMAD3, FOXA1, ZNF205, HOXB13, ERG, KDM1A, RELA, CREBBP, ZXDC, GATA4, ARNT, PBX4, GATA3, SMARCE1, PAX5, FOXM1, NKX3-1, FOS, GATA1, NR3C1, CEBPB, GFI1B, TEAD1, NR2F2, ESR1, HNF1B, GRHL2, MYOD1, TRPS1, ELF3, TCF12, BAF155, NIPBL, EP300, AR, GATA6, DPF2, HDAC2, GATA2, SIX2, ASH2L, NCOR1, BRD4, CTBP2, FOXP1, TEAD4, ZNF24, PDX1, AHR

Target gene symbol (double-evidenced CRMs): CLIC6,RUNX1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000159212, ENSG00000159216,

eachgene

Deatailed information for cohesin site CDBP00418074