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Basic information

CohesinDB ID: CDBP00418075

Locus: chr21-35385712-35386414

Data sourse: GSE206145, GSE206145-NatGen2015

Cell type: RPE, Fibroblast

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: Rad21

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 81% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 91%, "14_ReprPCWk": 6%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: TRP47, POU2F2, MAFG, FOSL1, ID3, XBP1, ZBTB48, WT1, MAFF, ZBTB33, MEF2C, PBX2, ZNF318, HOXC5, RELA, ZNF384, OGG1, ATF3, MYC, SMARCA4, ARID1B, SP140, GRHL3, TP63, NFE2, CEBPB, ZNF592, NFE2L2, OCA2, C11orf30, MAFK, SPI1, RNF2, BRD4, JUND, ILF3, SCRT1, ZNF316

Target gene symbol (double-evidenced CRMs): CLIC6,RUNX1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000159212, ENSG00000159216,

eachgene

Deatailed information for cohesin site CDBP00418075