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Basic information

CohesinDB ID: CDBP00418076

Locus: chr21-35390026-35390708

Data sourse: ENCSR000EFJ, GSE111913, ENCSR000BLY, GSE206145, GSE101921, GSE85526, GSE206145-NatGen2015, ENCSR000EHX, GSE68388, GSE83726, GSE116344

Cell type: RPE, HMEC, Fibroblast, RH4, HEKn, HCAEC, IMR-90, SK-N-SH, RT-112, HuCC-T1

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 4% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.889

Subunit: SA1,Rad21,SMC1,SA2,Mau2

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 81% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 71%, "7_Enh": 13%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: POU2F2, SMC1A, FOXA2, NKX2-2, MYCN, SIN3A, ZFX, STAG2, TEAD4, NME2, FOXA1, HOXB13, TWIST1, HOXC5, ERG, RELA, KDM1A, ZNF384, ETS1, NFIC, MYC, RUNX2, RAD21, PBX4, NRF1, GATA3, BATF3, GABPA, STAT3, PBX3, MAX, NKX3-1, FOS, TAL1, CDK8, MAFB, TP63, MED1, ARNTL, KLF4, MYOG, CEBPB, NR3C1, MYB, NEUROG2, KDM5B, ESR1, GRHL2, MYOD1, JUN, ZHX2, TCF12, EP300, AR, BRD4, SMC1, ZIM3, PDX1, FOSL2

Target gene symbol (double-evidenced CRMs): CLIC6,RUNX1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000159212, ENSG00000159216,

eachgene

Deatailed information for cohesin site CDBP00418076