Browse_each

Basic information

CohesinDB ID: CDBP00418079

Locus: chr21-35397987-35402508

Data sourse: ENCSR230ZWH, ENCSR000FAD, ENCSR000BSB, ENCSR000EGW, GSE131606, ENCSR330ELC, ENCSR000BUC, ENCSR000DYE, ENCSR917QNE, GSE115602, GSE139435, GSE93080, GSE67783, GSE86191, GSE101921, ENCSR806UKK, GSE51234, GSE120943, ENCSR198ZYJ, GSE112028, GSE130135, ENCSR199XBQ, GSE94872, ENCSR895JMI, GSE118494, ENCSR000EEG, ENCSR338DUC, GSE130140, GSE168045, ENCSR247LSH, GSE105004, ENCSR676MJK, GSE155324, ENCSR054FKH, GSE83726, GSE126755, ENCSR748MVX, ENCSR000ECS, GSE131577, ENCSR000BLD, GSE38411, GSE104888, GSE132649, GSE103477, GSE108869, GSE143937, GSE138405, GSE135093, GSE106870, ENCSR193NSH, GSE206145, GSE85526, ENCSR000ECE, ENCSR620NWG, ENCSR767DFK, ENCSR984DZW, GSE55407, ENCSR000BTQ, GSE129526, ENCSR537EFT, ENCSR760NPX, ENCSR000BLY, ENCSR150EFU, GSE121355, GSE111537, GSE25021, ENCSR000EAC, GSE76893, GSE145327, GSE76815, ENCSR000BMY, ENCSR000EHX, ENCSR635OSG, GSE97394, ENCSR217ELF, GSE38395, GSE131956, GSE110061, ENCSR000HPG, GSE111913, ENCSR335RKQ, ENCSR000EDE, GSE50893, ENCSR481YWD, GSE73207, GSE206145-GSE177045, GSE72082, ENCSR501LQA, GSE116868, ENCSR404BPV, GSE105028, ENCSR000EDW, GSE165895, ENCSR000EFJ, ENCSR000BTU, ENCSR000DZP, ENCSR000BKV, GSE152721, GSE206145-NatGen2015, GSE138105, ENCSR703TNG, GSE116344, GSE98367, ENCSR768DOX, ENCSR879KXD, ENCSR000BLS, ENCSR000EHW, GSE155828, ENCSR981FDC, ENCSR807WAC, GSE62063, ENCSR495WGO, ENCSR167MTG, ENCSR853VWZ, ENCSR956LGB, ENCSR944ZCT, ENCSR153HNT, GSE68388, GSE126990

Cell type: GM2610, CUTLL1, B-cell, Fibroblast, GM12890, BCBL-1, HFFc6, SNYDER, GM18505, MB157, GM12878, SK-N-SH, GM19193, Ramos, MCF-7, Hela-Kyoto, HEK293T, HCAEC, OCI-AML-3, GM10847, SLK, GP5d, GM2630, HEKn, hLCL, IMR-90, GM18486, DKO, H1-hESC, Monocytes, TF-1, CNCCs-H9ESC, HeLa-Tet-On, THP-1, HUES64, SC, HeLa, Neutrophil, CVB-hiPSC, CVI-hiPSC, Liver, H9-hESC, HeLa-S3, GM2255, GM18526, Lymphoblast, GM12891, GM2588, GBM39, GM19239, RT-112, Macrophage, GM12892, HCT-116, MCF-10A, Hep-G2, Neurons-H1, HUVEC, HSPC, HAP1, MDM, RH4, GM19240, Transformed-RPE1, HuCC-T1, RPE, HMEC, Ishikawa, K-562, Leukemia-SEM, GM19099, T-47D, HL-60, A-549, GM19238, CNCC-WT33iPSC, GM18951

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 83% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.133

Subunit: NIPBL,SA1,Rad21,SMC1,SMC3ac,SA2,Mau2,SMC3

CTCF binding site: CTCF CTCF motif: True

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 81% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 33%, "7_Enh": 26%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: NFIA, FOSL1, PGR, HMG20A, ZNF660, SOX2, MEIS2, FOXA1, RXRB, PBX2, KDM3A, SIN3B, HDGF, ATF3, ZBTB44, PRDM1, ATF4, ZNF189, TP63, CDX2, JMJD1C, MAF, TEAD1, TRIM28, BCLAF1, KLF6, ELF1, NFE2L2, ZNF573, ZNF217, ESR1, HNF1B, OCA2, HDAC8, ZNF561, JUN, TCF12, CTCF, BAF155, E4F1, EP300, LMO1, GATA6, SOX5, DPF2, SIX5, IRF4, TRIM24, RFX5, SOX6, DEK, DDX20, E2F1, SMC1, ZNF280A, TEAD4, KMT2B, FOXA3, GATAD2A, PDX1, RBPJ, TFAP2C, EED, NANOG, MYCN, POU5F1, CDK7, ZNF263, RUNX1T1, CTBP1, MTA2, DUX4, ZBTB48, STAT1, SRF, GATAD1, SAP130, NBN, ARID3A, ERG, HOXC5, MYC, SMARCA4, ARID1B, RAD21, RXRA, NKX2-1, PROX1, GABPA, STAT3, ZNF614, NKX3-1, IKZF1, NFE2, MIER3, RCOR1, NFRKB, NR2F6, NR3C1, CEBPB, ESRRA, STAT5B, KMT2A, CREB1, EZH2, TBL1XR1, ZNF652, ZHX2, SPI1, ZNF664, MIXL1, TFE3, IRF1, EHF, HDAC2, GATA2, GATAD2B, DRAP1, ZGPAT, SMARCA5, EP400, NFIL3, CC2D1A, RUNX1, THAP11, CTNNB1, SMC1A, BCL6, HDAC1, NKX2-2, CEBPA, CBX1, SOX13, AFF4, SMAD3, ZNF654, TRIM22, SMARCC1, RARA, ZBTB2, NOTCH1, ZNF35, BRD9, RUNX2, GATA4, ZNF184, ARNT, DAXX, ATF2, ZEB2, NFYA, PBX3, FOXM1, CHD1, CDK8, FOS, HMGXB4, MED1, ZEB1, TEAD3, PML, MYB, TERF1, PIAS1, SMAD1, C11orf30, L3MBTL2, NCOA1, MAFK, SP1, NIPBL, BCL11A, HNF4A, ARID2, REST, RBM25, ATF7, POU2F3, ASH2L, ZHX1, PHIP, AFF1, TCF3, FOXP1, BCOR, SMC3, ELL2, STAG1, MLLT1, STAG2, NFATC3, SKI, FOXA2, MTA3, CBX3, E2F8, MIER2, ZSCAN16, GTF2B, MAFF, ZNF692, MEF2C, CDK9, HOXB13, ZNF580, KDM1A, YY1, RELA, JUNB, TCF4, SKIL, HIF1A, GATA3, TAL1, MAX, GATA1, ZSCAN26, ZNF143, TLE3, KLF4, ZNF592, CEBPG, GFI1B, NR2F2, KDM5B, TP53, NFKB1, ELF3, BRD2, KAT8, TBX21, ARID4B, AR, NFKBIZ, ZNF579, ZBTB40, EGLN2, HSF1, RNF2, ZBTB26, BRD4, ILF3, JUND, CLOCK, MAZ, ZNF24, DMAP1, FOSL2

Target gene symbol (double-evidenced CRMs): RUNX1,CLIC6,SETD4,SMIM11A

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000205670, ENSG00000159212, ENSG00000159216, ENSG00000185917,

eachgene

Deatailed information for cohesin site CDBP00418079