Browse_each

Basic information

CohesinDB ID: CDBP00418085

Locus: chr21-35411186-35412282

Data sourse: GSE86191, ENCSR000EHW, GSE206145-NatGen2015, GSE206145, ENCSR153HNT

Cell type: RPE, Fibroblast, HCT-116, SK-N-SH, K-562

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 2% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.944

Subunit: SMC3,Rad21,SA2,SA1

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 81% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 70%, "14_ReprPCWk": 26%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RUNX1, TRP47, CEBPA, POU5F1, MYCN, ZFX, XBP1, ZBTB48, WT1, ERG, YY1, RELA, OGG1, NFIC, CDK6, SP140, NFIB, HIF1A, ARNT, GRHL3, CBFB, STAT3, MED1, KDM5B, AR, RXR, AATF, SMC3

Target gene symbol (double-evidenced CRMs): SMIM11A,RUNX1,CLIC6,SETD4

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000205670, ENSG00000159212, ENSG00000159216, ENSG00000185917,

eachgene

Deatailed information for cohesin site CDBP00418085