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Basic information

CohesinDB ID: CDBP00418086

Locus: chr21-35417009-35417597

Data sourse: GSE138405, GSE126990, GSE108869, ENCSR000EDE

Cell type: HeLa-S3, Hela-Kyoto

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: SMC3,Rad21,SA2

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 81% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 73%, "14_ReprPCWk": 22%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: PGR, FOXA1, PBX2, ATF3, PRDM1, HDAC3, ESR1, BAF155, EP300, GATA6, DPF2, TRIM24, IRF4, RFX5, SOX6, ZNF350, TEAD4, TFAP2C, POU2F2, NANOG, CHD8, DUX4, STAT1, ERG, MYC, ARID1B, RAD21, GABPA, STAT3, NKX3-1, IKZF1, RCOR1, NR3C1, CEBPB, ZNF750, CREB1, GRHL2, HDAC2, GATA2, ZNF146, ATF1, RUNX1, MAFG, SMARCC1, GATA4, GR, ARNT, ZEB2, CBFA2T3, FOS, MED1, PML, CEBPD, MYB, SCRT2, PIAS1, SMAD1, ZMYM3, C11orf30, MAFK, BCL11A, RBM25, CCNT2, ASH2L, FOXP1, SMC3, CBFA2T2, MAFF, HOXB13, RELA, GATA3, TAL1, MAX, NRIP1, GATA1, ZNF143, TLE3, KLF4, TCF7L2, AR, RNF2, NCOR1, BRD4, SCRT1, ZNF316

Target gene symbol (double-evidenced CRMs): CLIC6,SMIM11A,RUNX1,SETD4

Function elements

Human SNPs: Basophil_percentage_of_white_cells

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000205670, ENSG00000159212, ENSG00000159216, ENSG00000185917,

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Deatailed information for cohesin site CDBP00418086