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Basic information

CohesinDB ID: CDBP00418088

Locus: chr21-35423373-35425369

Data sourse: GSE67783, GSE86191, GSE206145, GSE206145-NatGen2015, ENCSR153HNT, GSE116344

Cell type: RPE, Fibroblast, RH4, HCT-116, K-562, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 5% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.933

Subunit: NIPBL,SA1,Rad21,SA2,Mau2

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 81% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 44%, "14_ReprPCWk": 27%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RUNX1, SMC1A, TOP2A, STAT1, MEF2C, SMARCC1, ZNF300, RELA, RUNX2, RAD21, TAL1, STAT3, FOS, MED1, NR3C1, CEBPB, CEBPG, TRIM28, CEBPD, ESR1, NFKB1, JUN, SPI1, IRF1, FLI1, BRD4, TEAD4

Target gene symbol (double-evidenced CRMs): RUNX1,SMIM11A,SETD4,CLIC6

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000205670, ENSG00000159212, ENSG00000159216, ENSG00000185917,

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Deatailed information for cohesin site CDBP00418088