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Basic information

CohesinDB ID: CDBP00418090

Locus: chr21-35427520-35430013

Data sourse: ENCSR000BLD, GSE67783, GSE86191, GSE98367, ENCSR000BLY, GSE105028, GSE206145-NatGen2015, GSE120943, ENCSR153HNT, GSE68388, GSE83726, GSE103477, GSE116344, GSE165895

Cell type: MDM, H1-hESC, Macrophage, Fibroblast, HCT-116, Monocytes, RH4, H9-hESC, SK-N-SH, K-562, HSPC, HuCC-T1, HFFc6

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 7% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.856

Subunit: SA1,Rad21,SMC1,SA2,Mau2

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 81% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 34%, "14_ReprPCWk": 24%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOXO1, PGR, XBP1, HLF, PBX2, MLL4, BMI1, NFIC, RUNX3, ZNF383, SMARCE1, MITF, SFPQ, ZNF467, JMJD1C, MAF, TEAD1, RBM39, LMO2, ESR1, OCA2, CTCF, TCF12, EP300, LMO1, TEAD4, KMT2B, NANOG, BRD1, POU5F1, MYCN, RUNX1T1, KDM4C, CDK7, CTBP1, ZBTB48, ZSCAN5A, ERG2, ERG, ETS1, MYC, EOMES, KDM4A, RAD21, FOXP2, GRHL3, RXRA, NKX2-1, PROX1, GABPA, STAT3, IKZF1, ARNTL, NR3C1, CEBPB, STAT5B, KMT2A, EZH2, SPI1, ZNF786, IRF1, RUNX1, SMC1A, CEBPA, EZH2phosphoT487, SIN3A, ZFX, SMAD3, CBX8, ERG3, TWIST1, PRDM10, ZNF384, NOTCH1, RUNX2, CDK6, SMAD2, ARNT, PBX3, FOS, CDK8, MED1, MYB, L3MBTL2, TBX5, USF1, BCL11A, REST, CTBP2, TCF3, STAG1, SKI, PPARG, MEIS1, WT1, MEF2C, TCF7, ZKSCAN1, RELA, JUNB, GATA3, TAL1, MAX, ZNF143, CBX2, CEBPG, BCL11B, NR2F2, TP53, PKNOX1, ZNF334, MYOD1, T, TBX21, BHLHE40, AR, HSF1, RNF2, NOTCH3, BRD4, MAZ

Target gene symbol (double-evidenced CRMs): SMIM11A

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000205670,

eachgene

Deatailed information for cohesin site CDBP00418090