- Basic information
- CohesinDB ID: CDBP00418091
- Locus: chr21-35431551-35432212
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Data sourse: ENCSR000BTQ, GSE72082, ENCSR000FAD, GSE98367, GSE138405, GSE129526, GSE206145-NatGen2015, GSE50893, ENCSR000EDE, GSE121355, GSE103477, ENCSR703TNG, GSE25021, GSE116344, ENCSR000ECS
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Cell type: MCF-7, MDM, Hela-Kyoto, Fibroblast, HCT-116, RH4, SNYDER, GM19240, HeLa-S3, K-562, GM19239, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 4% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.867
- Subunit: SMC3,Rad21,SA1,SMC1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
81% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"9_Het": 53%,
"15_Quies": 28%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: PAX8, MAFG, GATA1, SMC1A, TRIM28, TRIM24, TOP2A, REST, RAD21, XBP1, ZNF317, OCA2, ESR1, DUX4, SETDB1, ZNF350, CTCF, NRIP1, ZNF143, STAG1
- Target gene symbol (double-evidenced CRMs): SMIM11A,RUNX1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 5
- Related genes and loops
- Related gene:
ENSG00000205670,
ENSG00000159216,
- Related loop:
chr21:34350000-34375000~~chr21:35425000-35450000,
chr21:34800634-34802701~~chr21:35431208-35432504,
chr21:35425000-35450000~~chr21:35600000-35625000,
chr21:35425000-35450000~~chr21:35825000-35850000,
chr21:35425000-35450000~~chr21:35950000-35975000,
chr21:35431113-35432519~~chr21:35507406-35509556,
chr21:35431152-35432481~~chr21:35939353-35941240,
chr21:35431177-35432375~~chr21:35838785-35841072,
chr21:35431208-35432504~~chr21:35838718-35841129,