- Basic information
- CohesinDB ID: CDBP00418092
- Locus: chr21-35436755-35437426
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Data sourse: ENCSR000BLD, GSE104888, ENCSR230ZWH, ENCSR000FAD, GSE72082, ENCSR000BSB, ENCSR000EGW, ENCSR000BLY, GSE105028, GSE121355, GSE131606, GSE108869, GSE25021, ENCSR917QNE, ENCSR000EFJ, GSE93080, ENCSR000BKV, GSE138405, GSE101921, GSE94872, ENCSR000EEG, GSE98367, ENCSR000BLS, GSE206145, GSE85526, ENCSR000ECE, GSE97394, GSE110061, GSE129526, GSE111913, ENCSR000EDE, ENCSR153HNT, GSE126990, GSE50893, ENCSR000ECS, GSE131577
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Cell type: GM19240, Liver, H9-hESC, HEKn, HeLa-S3, GM2255, IMR-90, K-562, GM18526, H1-hESC, GM18505, GM12878, GM12891, GM2588, SK-N-SH, GM19239, RT-112, GM19193, GM19099, HUES64, Macrophage, GM12892, MCF-7, Hela-Kyoto, HCT-116, HL-60, HEK293T, Hep-G2, HUVEC, HCAEC, GM19238
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 13% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.656
- Subunit: SA1,Rad21,SMC1,SA2,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
81% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 73%,
"14_ReprPCWk": 20%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: ZNF384, ZNF22, REST, SMC1A, SCRT2, RAD21, SCRT1, ILF3, ZEB2, SMC1, DDX5, SMC3, CTCF, STAG1
- Target gene symbol (double-evidenced CRMs): SMIM11A
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000205670,
- Related loop:
chr21:34350000-34375000~~chr21:35425000-35450000,
chr21:34800634-34802701~~chr21:35431208-35432504,
chr21:35425000-35450000~~chr21:35600000-35625000,
chr21:35425000-35450000~~chr21:35825000-35850000,
chr21:35425000-35450000~~chr21:35950000-35975000,
chr21:35431113-35432519~~chr21:35507406-35509556,
chr21:35431152-35432481~~chr21:35939353-35941240,
chr21:35431177-35432375~~chr21:35838785-35841072,
chr21:35431208-35432504~~chr21:35838718-35841129,