- Basic information
- CohesinDB ID: CDBP00418103
- Locus: chr21-35470408-35470913
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Data sourse: ENCSR000BLD, GSE98367, ENCSR879KXD, GSE105028, ENCSR000ECE, ENCSR153HNT, GSE68388, GSE103477, GSE97394, GSE64758
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Cell type: MDM, H1-hESC, Macrophage, H9-hESC, K-562, HuCC-T1, HUES64
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.922
- Subunit: NIPBL,SA1,Rad21,SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
81% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 67%,
"7_Enh": 14%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOSL1, SOX2, FOXA1, PBX2, ATF3, CHD7, SMARCE1, ELF1, TRIM28, ESR1, OCA2, JUN, CTCF, EP300, E4F1, MNT, DPF2, RYBP, E2F6, TRIM24, SOX6, CREB3, TEAD4, EHMT2, NANOG, POU2F2, MYCN, POU5F1, ID3, CTBP1, MTA2, STAT1, MYC, EZH1, SMARCA4, ARID1B, RAD21, GRHL3, IKZF1, RCOR1, LEF1, NR2F6, ESRRA, CEBPB, CREB1, TBL1XR1, SPI1, IRF1, HDAC2, GATA2, ZNF644, NR2C2, EP400, ATF1, BCL6, SMC1A, HDAC1, ZFX, SMAD3, RUNX2, CDK6, GATA4, BACH1, ZEB2, HMBOX1, CBFA2T3, NR2C1, CDK8, GMEB1, DIDO1, CEBPD, L3MBTL2, USF1, BCL11A, NIPBL, SP1, NKX2-5, ZBTB7A, ATF7, POU2F3, ASH2L, CTBP2, BCOR, FOXP1, STAG1, CBX3, MTA3, CREM, WT1, HOXB13, RELA, ZNF148, CHAMP1, ZNF830, GATA3, MGA, MAX, GATA1, HAND2, CEBPG, ZNF592, NCOA3, NR2F2, NR2F1, T, BHLHE40, ZBTB40, MYNN, RNF2, NCOR1, JUND, BRD4, MAZ
- Target gene symbol (double-evidenced CRMs): CLIC6
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 4
- Related genes and loops