- Basic information
- CohesinDB ID: CDBP00418106
- Locus: chr21-35473456-35474136
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Data sourse: GSE103477, GSE120943, GSE98367
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Cell type: MDM, Monocytes, Macrophage, THP-1
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: Rad21,SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
81% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 61%,
"5_TxWk": 20%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, SMC1A, POU5F1, NME2, STAT1, ZNF662, MEF2C, ZNF770, CDK9, RELA, IRF2, RAD21, TAL1, IKZF1, CDK8, CEBPB, JMJD1C, KMT2A, MYB, TCF7L2, SMAD1, ZMYM3, ZNF334, STAT5A, PHOX2B, SPI1, IRF1, TRIM24, BRD4, MLLT1
- Target gene symbol (double-evidenced CRMs): CLIC6
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 1
- Related genes and loops