- Basic information
- CohesinDB ID: CDBP00418126
- Locus: chr21-35530738-35531191
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Data sourse: GSE103477, GSE111537, GSE120943, GSE98367
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Cell type: MDM, OCI-AML-3, Monocytes, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: Rad21,SA2,SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
80% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 84%,
"14_ReprPCWk": 9%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, TRIM25, PGR, MEIS2, XBP1, HNF1A, FOXA1, PBX2, ATF3, RUNX3, ATF4, CBFB, PAX5, TP63, BACH2, CDX2, JMJD1C, MAF, ELF1, TRIM28, BCLAF1, SNAI2, LMO2, ESR1, OCA2, MLL, HNF1B, CTCF, TCF12, KLF1, GATA6, DPF2, TRIM24, IRF4, CREB3, E2F1, ZNF677, KMT2B, PDX1, TFAP2C, EED, POU2F2, CHD8, ZNF263, MYCN, RUNX1T1, POU5F1, KDM4C, CTBP1, DUX4, ZBTB48, STAT1, ZNF205, ERG, PBX1, ETS1, MYC, ONECUT1, SMARCA4, ARID1B, RAD21, GRHL3, RXRA, STAT3, XRCC5, IKZF1, RCOR1, TERF2, NR2F6, VDR, NR3C1, CEBPB, ESRRA, STAT5B, KMT2A, CREB1, EZH2, ZHX2, SPI1, IRF1, GATA2, SIX2, FLI1, HCFC1, NCOA2, ATF1, RUNX1, BCL6, SMC1A, CEBPA, NKX2-2, HDAC1, SOX13, ZFX, NFKBIA, TET2, ZBTB2, RARA, NOTCH1, IRF2, ZNF384, RUNX2, GATA4, ARNT, ATF2, PBX3, FOS, CDK8, CHD1, SUPT5H, MED1, TERF1, MYB, SCRT2, L3MBTL2, BCL11A, NR4A1, HNF4A, REST, ZBTB7A, ATF7, ASH2L, HNRNPLL, TCF3, BCOR, SMC3, MLLT1, STAG1, PPARG, TBL1X, MTA3, CREM, MEIS1, EBF1, FOXA2, GTF2B, WT1, MEF2C, CDK9, KDM1A, YY1, RELA, JUNB, SP140, ZIC2, HIF1A, BATF, MAX, GATA1, KLF4, BCL11B, CEBPG, NCOA3, NR2F1, KDM5B, PKNOX1, MED, ZNF334, MYOD1, ELF3, BRD2, AR, TAF1, ZBTB40, RXR, EGR1, HSF1, RNF2, NOTCH3, JUND, BRD4, ILF3, MAZ, ZNF24
- Target gene symbol (double-evidenced CRMs): SMIM11A
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops