- Basic information
- CohesinDB ID: CDBP00418128
- Locus: chr21-35547814-35549182
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Data sourse: ENCSR153HNT, ENCSR879KXD
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Cell type: K-562
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.989
- Subunit: SA1,Rad21
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
80% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 70%,
"14_ReprPCWk": 16%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOSL1, HMGN3, FOXA1, PBX2, HDGF, ATF3, THRB, NFIC, ZC3H8, ATF4, CBFB, ZNF189, SMARCE1, HDAC3, CDX2, ZNF629, TEAD1, TRIM28, NFE2L2, ESR1, HDAC8, JUN, TCF12, CTCF, EP300, E4F1, MNT, GATA6, DPF2, E2F6, TRIM24, CREB3, SOX6, DDX20, E2F1, ZNF350, TEAD4, EHMT2, ID3, CTBP1, MTA2, ZSCAN21, STAT1, HINFP, NONO, NBN, ARID3A, TBP, HNF4G, USP7, SMARCC2, MYC, SMARCA4, ARID1B, GRHL3, RXRA, NKX2-1, FOXK2, ZNF8, XRCC5, STAT3, IKZF1, LEF1, RCOR1, ZNF639, NR2F6, NFRKB, NR3C1, CEBPB, ESRRA, ZBTB11, TBL1XR1, EZH2, KLF8, GRHL2, SPI1, IRF1, HDAC2, GATA2, ZNF644, EP400, ATF1, RUNX1, MAFG, HDAC1, LDB1, SOX13, SMAD3, ZMIZ1, PRDM10, IRF2, BRD9, RUNX2, OSR2, ZNF184, ARNT, BACH1, TFDP1, PBX4, ATF2, HMBOX1, ZEB2, CBFA2T3, FOXM1, NR2C1, CDK8, MED1, PML, CEBPD, SMAD1, ZNF3, C11orf30, L3MBTL2, NCOA1, SETDB1, STAT5A, KLF16, BCL11A, NR4A1, HNF4A, REST, ZBTB7A, RBM25, CCNT2, ATF7, AFF1, THRA, PHIP, STAT2, MLLT1, PTTG1, ZNF394, CBFA2T2, KLF13, CBX3, MTA3, FOXA2, CREM, RBBP5, ZNF589, RELA, JUNB, NEUROD1, CHAMP1, MGA, TAL1, MAX, GATA1, MTA1, CEBPG, ZNF592, NR2F2, ZNF83, NR2F1, AR, PTRF, ZBTB40, ZNF366, MYNN, RNF2, NCOR1, JUND, ILF3, BRD4, IRF9, ZNF24, ADNP
- Target gene symbol (double-evidenced CRMs): SMIM11A
- Function elements
- Human SNPs: Liver_enzyme_levels_(alkaline_phosphatase)
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops