- Basic information
- CohesinDB ID: CDBP00418132
- Locus: chr21-35563021-35566189
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Data sourse: ENCSR230ZWH, GSE72082, ENCSR000BLY, GSE103477, GSE111537, GSE25021, GSE165895, ENCSR000EFJ, GSE67783, GSE86191, GSE206145-NatGen2015, GSE135093, GSE130135, ENCSR703TNG, GSE98367, ENCSR879KXD, ENCSR000EHW, ENCSR000EHX, GSE131956, ENCSR000HPG, GSE111913, ENCSR153HNT, GSE68388, GSE83726
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Cell type: MCF-7, Macrophage, Fibroblast, HCT-116, RH4, HEK293T, THP-1, RT-112, GBM39, IMR-90, SK-N-SH, K-562, Liver, OCI-AML-3, HSPC, HuCC-T1, HFFc6
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 11% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.811
- Subunit: NIPBL,SA1,Rad21,SMC1,SA2,Mau2,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
80% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 34%,
"7_Enh": 29%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: AR, MED1, NR3C1, ESRRA, GATA2, CEBPB, RUNX2, BRD3, SCRT2, NCOR1, GRHL3, BRD4, SCRT1, TAL1, ZNF513, GATA1, SPI1
- Target gene symbol (double-evidenced CRMs): SMIM11A
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops