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Basic information

CohesinDB ID: CDBP00418136

Locus: chr21-35576556-35580249

Data sourse: ENCSR000EFJ, GSE138405, ENCSR000HPG, ENCSR000BLY, GSE206145, GSE206145-NatGen2015, GSE120943, GSE112028, GSE126990, ENCSR000ECS, GSE165895

Cell type: Hela-Kyoto, Fibroblast, Monocytes, HEK293T, HeLa-S3, IMR-90, SK-N-SH, HeLa-Tet-On, HFFc6

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 8% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.900

Subunit: NIPBL,SA1,Rad21,SMC1,SMC3ac,SA2,Mau2,SMC3

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 80% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 53%, "14_ReprPCWk": 21%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RELA, NCOA3, RUNX2, MCM5, BRD3, NR2F1, GRHL3, ZNF334, BRD2, HNF4A

Target gene symbol (double-evidenced CRMs): CLIC6,SMIM11A,RUNX1,SETD4

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000205670, ENSG00000159212, ENSG00000159216, ENSG00000185917,

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Deatailed information for cohesin site CDBP00418136