- Basic information
- CohesinDB ID: CDBP00418145
- Locus: chr21-35600876-35601492
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Data sourse: GSE206145-NatGen2015
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Cell type: Fibroblast
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 0% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.989
- Subunit: Mau2
-
CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
80% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 55%,
"14_ReprPCWk": 34%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: TOP2A, XBP1, GTF2B, WT1, DUX4, FOXA1, CBX8, SUZ12, HOXB13, ERG, BMI1, NFIC, RUNX2, GATA4, GRHL3, GATA3, ATF2, GABPA, STAT3, TAL1, PBX3, XRCC5, GATA1, ZNF143, NR3C1, CEBPB, NCOA3, NR2F2, EZH2, ESR1, PHOX2B, CTCF, TCF12, USF1, EP300, AR, TAF1, GATA2, REST, POU2F3, ATF7, RNF2, NCOR1, JUND, E2F1, RELB, AHR
- Target gene symbol (double-evidenced CRMs): RCAN1,RUNX1,SMIM11A,CLIC6
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 2
- Related genes and loops
- Related gene:
ENSG00000205670,
ENSG00000159200,
ENSG00000159212,
ENSG00000159216,
- Related loop:
chr21:34350000-34375000~~chr21:35575000-35600000,
chr21:34350000-34375000~~chr21:35600000-35625000,
chr21:34500000-34525000~~chr21:35600000-35625000,
chr21:34675000-34700000~~chr21:35575000-35600000,
chr21:34675000-34700000~~chr21:35600000-35625000,
chr21:34725000-34750000~~chr21:35600000-35625000,
chr21:34744610-34746779~~chr21:35602844-35604275,
chr21:34750000-34775000~~chr21:35600000-35625000,
chr21:34875000-34900000~~chr21:35575000-35600000,
chr21:34875000-34900000~~chr21:35600000-35625000,
chr21:35250000-35275000~~chr21:35575000-35600000,
chr21:35400000-35425000~~chr21:35575000-35600000,
chr21:35400000-35425000~~chr21:35600000-35625000,
chr21:35425000-35450000~~chr21:35600000-35625000,
chr21:35450000-35475000~~chr21:35575000-35600000,
chr21:35575000-35600000~~chr21:35825000-35850000,
chr21:35575000-35600000~~chr21:36025000-36050000,
chr21:35600000-35625000~~chr21:35925000-35950000,