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Basic information

CohesinDB ID: CDBP00418146

Locus: chr21-35602765-35603978

Data sourse: ENCSR000BLD, GSE206145-GSE177045, GSE104888, ENCSR230ZWH, GSE72082, ENCSR000BSB, GSE116868, ENCSR000EGW, ENCSR000BLY, GSE105028, GSE121355, GSE131606, GSE25021, GSE115602, ENCSR917QNE, GSE93080, GSE143937, GSE67783, ENCSR000BKV, GSE86191, GSE138405, GSE76893, GSE206145-NatGen2015, ENCSR703TNG, GSE106870, ENCSR000BLS, ENCSR000ECE, GSE97394, ENCSR000BTQ, GSE110061, GSE129526, GSE111913, ENCSR054FKH, ENCSR000EDE, ENCSR153HNT, GSE68388, GSE83726, GSE50893, ENCSR000ECS

Cell type: RH4, GM19240, CVI-hiPSC, Liver, HuCC-T1, H9-hESC, Fibroblast, HeLa-S3, K-562, DKO, H1-hESC, MB157, GM12878, SK-N-SH, GM19239, RT-112, HUES64, MCF-7, Hela-Kyoto, HCT-116, Hep-G2, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 14% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.756

Subunit: SA1,Rad21,SMC1,SA2,SMC3

CTCF binding site: CTCF CTCF motif: True

Genomic location: TSS,TES

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 80% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 49%, "14_ReprPCWk": 33%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: TBL1X, MYCN, FLI1, CLOCK, CTCF, ZNF449, SPI1, STAG1, ERG

Target gene symbol (double-evidenced CRMs): RUNX1,CLIC6,RCAN1,SMIM11A

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 5

Related genes and loops

Related gene: ENSG00000205670, ENSG00000159200, ENSG00000159212, ENSG00000159216,

eachgene

Deatailed information for cohesin site CDBP00418146