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Basic information

CohesinDB ID: CDBP00418147

Locus: chr21-35604344-35604583

Data sourse: GSE206145, GSE86191

Cell type: RPE, HCT-116

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: Rad21

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: TSS,TES

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 80% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 54%, "14_ReprPCWk": 34%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: NCOA2, GLIS1, RUNX1, NANOG, SMC1A, MYCN, POU5F1, SOX2, ZFX, TEAD4, ZBTB48, WT1, SMAD3, ZSCAN5A, HLF, ZNF770, ERG3, TET2, CDK9, HNF4G, KDM1A, YY1, RELA, ZBTB2, ZNF35, ASCL1, ATF3, MYC, EZH1, ZFP64, RAD21, CHD7, ZIC2, SP140, GRHL3, ATF2, MAX, XRCC5, NRIP1, ZNF143, PLAG1, CDX2, ZNF750, ESRRA, NR2F2, SCRT2, CREB1, NR2F1, EZH2, LMO2, ESR1, NCOA1, ZNF334, MYOD1, CTCF, TCF12, USF1, EP300, HNF4A, AR, ZBTB20, GATA6, GATA2, E2F6, ZBTB42, NOTCH3, BRD4, ZNF423, JUND, MAZ, SMC1, NFIL3, SMC3, STAG1, TFAP2C

Target gene symbol (double-evidenced CRMs): RCAN1,RUNX1,CLIC6,SMIM11A

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 1

Related genes and loops

Related gene: ENSG00000205670, ENSG00000159200, ENSG00000159212, ENSG00000159216,

eachgene

Deatailed information for cohesin site CDBP00418147