- Basic information
- CohesinDB ID: CDBP00418149
- Locus: chr21-35606136-35607050
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Data sourse: GSE101921, ENCSR000BLY
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Cell type: HMEC, SK-N-SH
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: Rad21,SA2
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
80% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 56%,
"14_ReprPCWk": 30%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, POU2F2, FOXA2, MYCN, CDK7, WT1, SMAD3, CDK9, RUNX2, SMARCA4, RAD21, PRDM1, GRHL3, PBX4, GATA3, PRDM9, BATF3, PBX3, SOX10, GATA1, CDK8, RCOR1, MITF, TRIM28, ETV1, NFE2L2, OCA2, GRHL2, ZNF334, SETDB1, PHOX2B, CTCF, BRD2, USF1, ZNF211, BRD4, MAZ, STAG2, TFAP2C, FOSL2
- Target gene symbol (double-evidenced CRMs): RUNX1,SMIM11A,CLIC6,RCAN1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000205670,
ENSG00000159200,
ENSG00000159212,
ENSG00000159216,
- Related loop:
chr21:34350000-34375000~~chr21:35600000-35625000,
chr21:34500000-34525000~~chr21:35600000-35625000,
chr21:34675000-34700000~~chr21:35600000-35625000,
chr21:34725000-34750000~~chr21:35600000-35625000,
chr21:34744610-34746779~~chr21:35602844-35604275,
chr21:34750000-34775000~~chr21:35600000-35625000,
chr21:34875000-34900000~~chr21:35600000-35625000,
chr21:35400000-35425000~~chr21:35600000-35625000,
chr21:35425000-35450000~~chr21:35600000-35625000,
chr21:35600000-35625000~~chr21:35925000-35950000,