- Basic information
- CohesinDB ID: CDBP00418151
- Locus: chr21-35611744-35612170
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Data sourse: GSE206145-NatGen2015, GSE165895
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Cell type: Fibroblast, HFFc6
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: Mau2,SMC1
-
CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
80% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 65%,
"14_ReprPCWk": 19%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RELA, PAX3-FOXO1, POU2F2, GATA2, PGR, MYC, POU2F3, CHD7, POU4F2, GRHL3, BRD4, GATA3, GABPA, TP63, GATA1, TFAP2C
- Target gene symbol (double-evidenced CRMs): RCAN1,RUNX1,CLIC6,SMIM11A
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000205670,
ENSG00000159200,
ENSG00000159212,
ENSG00000159216,
- Related loop:
chr21:34350000-34375000~~chr21:35600000-35625000,
chr21:34500000-34525000~~chr21:35600000-35625000,
chr21:34675000-34700000~~chr21:35600000-35625000,
chr21:34692384-34694384~~chr21:35615361-35617172,
chr21:34722101-34723694~~chr21:35615336-35617186,
chr21:34725000-34750000~~chr21:35600000-35625000,
chr21:34744530-34746777~~chr21:35614293-35617009,
chr21:34744561-34746765~~chr21:35615361-35617172,
chr21:34744567-34746780~~chr21:35615336-35617206,
chr21:34744589-34746918~~chr21:35615292-35617215,
chr21:34744771-34746620~~chr21:35615456-35617044,
chr21:34744787-34746612~~chr21:35615562-35617011,
chr21:34744840-34746785~~chr21:35615343-35617201,
chr21:34744884-34746937~~chr21:35615517-35617148,
chr21:34750000-34775000~~chr21:35600000-35625000,
chr21:34875000-34900000~~chr21:35600000-35625000,
chr21:34887476-34892097~~chr21:35614293-35617009,
chr21:34887508-34892091~~chr21:35615361-35617172,
chr21:34887510-34891018~~chr21:35615456-35617044,
chr21:34887533-34888841~~chr21:35614050-35617694,
chr21:34888177-34892032~~chr21:35615399-35616943,
chr21:34889184-34892059~~chr21:35615365-35617187,
chr21:34889215-34891491~~chr21:35615343-35617201,
chr21:34889427-34892109~~chr21:35614047-35617200,
chr21:35050390-35052342~~chr21:35614293-35617009,
chr21:35400000-35425000~~chr21:35600000-35625000,
chr21:35425000-35450000~~chr21:35600000-35625000,
chr21:35600000-35625000~~chr21:35925000-35950000,