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Basic information

CohesinDB ID: CDBP00418153

Locus: chr21-35618320-35620072

Data sourse: ENCSR000EFJ, GSE138405, ENCSR000HPG, ENCSR000BLY, GSE206145, GSE85526, GSE206145-NatGen2015, ENCSR000EDE, GSE68388, GSE131606, ENCSR000ECS, GSE165895

Cell type: Hela-Kyoto, Fibroblast, HEKn, HEK293T, HeLa-S3, IMR-90, SK-N-SH, HFFc6, HuCC-T1, DKO

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 6% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.889

Subunit: SA1,Rad21,SMC1,SA2,Mau2,SMC3

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 80% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 61%, "14_ReprPCWk": 14%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOSL1, SOX2, XBP1, PBX2, ATF3, NFIC, CHD7, PRDM1, ATF4, ZNF189, TEAD1, NFE2L2, JUN, TCF12, EP300, GATA6, DPF2, SOX4, TRIM24, SOX6, E2F1, TEAD4, EHMT2, TOP2A, ID3, CTBP1, ZSCAN21, ZBTB17, HOXC5, ZBTB21, ERG, ETS1, SMARCA4, ARID1B, RAD21, LHX2, GRHL3, NKX2-1, BATF3, GABPA, STAT3, IKZF1, NFE2, RCOR1, VDR, NR3C1, CEBPB, ZNF750, CREB1, ZHX2, SPI1, EHF, GATA2, FLI1, ATF1, SMC1A, MAFG, HDAC1, SMAD3, SMARCC1, RUNX2, GATA4, ZNF184, PBX4, ATF2, HMBOX1, ZEB2, PBX3, CBFA2T3, FOS, MED1, MYB, C11orf30, MAFK, REST, SMC3, MLLT1, ZNF600, ZNF692, ZNF662, RELA, JUNB, HIF1A, GATA3, MAX, CEBPG, NR2F1, TP53, PKNOX1, MYOD1, ELF3, BHLHE40, RNF2, BRD4, JUND, ZNF24, ZNF316, FOSL2

Target gene symbol (double-evidenced CRMs): RCAN1,CLIC6,SMIM11A,RUNX1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000205670, ENSG00000159200, ENSG00000159212, ENSG00000159216,

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Deatailed information for cohesin site CDBP00418153