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Basic information

CohesinDB ID: CDBP00418156

Locus: chr21-35624757-35626689

Data sourse: GSE138405, ENCSR000EDE, GSE83726, GSE116344, GSE126990

Cell type: HeLa-S3, Hela-Kyoto, RH4

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 2% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.967

Subunit: SA1,Rad21,SMC3,SA2,SMC3ac

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 80% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 60%, "14_ReprPCWk": 26%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOXA2, TOP2A, POU4F2, ZBTB48, DUX4, FOXA1, CBX8, RELA, MYC, ZNF184, NRF1, PBX4, ARNT, NKX2-1, GATA3, PBX3, MAX, UBN1, CDK8, NR3C1, CEBPB, ETV1, TCF7L2, ESR1, MYOD1, TCF12, SP1, MNT, AR, PAX8, GATA2, SIX2, FLI1, SCRT1, BRD4, JUND, SMC3, ELL2, TFAP2C

Target gene symbol (double-evidenced CRMs): SETD4,RUNX1,CLIC6,SMIM11A,RCAN1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000205670, ENSG00000159200, ENSG00000159212, ENSG00000159216, ENSG00000185917,

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Deatailed information for cohesin site CDBP00418156